Intravenous amino acids for kidney protection in patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized controlled trials.

J Int Med Res · 2025 · PMC11792033 · PMID 39901806

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

However, since the results did not reach statistical significance, this conclusion cannot be made and further large scale RCTs are needed to make definitive conclusions.

also in 50,127 other papers

likely to be significantno p-value reported

24 The exact mechanisms causing this vasodilation are not fully understood but evidence indicates that neither the direct vasodilatory effects of amino acids on the blood vessels, nor their metabolism in the liver or the release of hormonal factors from the liver, are likely to be significant contributors.

also in 468 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.