Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179.

Nat Commun · 2025 · PMC11794477 · PMID 39904981

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0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

showed a trendp = 0.057so close (0.05 < p ≤ 0.1)

CT-179-treated tumors showed a trend to decreased p-OLIG2 (p = 0.057), consistent with disruption of OLIG2 dimerization, and significantly reduced p-RB, indicating an overall decrease in proliferation (Fig. 5A ).

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