Evaluation of co‑inhibition of ErbB family kinases and PI3K for HPV‑negative head and neck squamous cell carcinoma.

Oncol Rep · 2025 · PMC11800064 · PMID 39886949

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did not reach statistical significanceno p-value reported

In summary, while afatinib or copanlisib alone had modest inhibitory effects on tumor growth, they did not reach statistical significance, whereas the combination of the two drugs significantly inhibited tumor growth.

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