Social isolation during adolescence differentially affects spatial learning in adult male and female mice.

Similarly, a two-way repeated measures ANOVA on latency to first enter the shock zone on trials 2–3 revealed an effect of trial that approached significance ( F (1,17) = 3.91, P = 0.06), with Bonferroni's multiple planned comparisons indicating that latency was lower in stressed males than controls on trial 2 ( P = 0.05) but not trial 3 ( P = 0.95) ( Fig. 2 F).

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