Exhaustion of CD8<sup>pos</sup> central memory regulatory T cell differentiation is involved in renal allograft rejection.

This is probably due to an increased differentiation of RTE Tregs via CD31 pos memory Tregs into CD31 neg memory Tregs ( Figure 2B , pathway 1), as RTE Tregs are reduced, independently of age, whereas CD31 neg memory Tregs and resting MN Tregs are almost significantly increased ( Figures 1F, I, J ).

also in 514 other papers

Compared to stable KTR, those who developed a rejection during the follow-up period showed a trend towards an increased proportion of CM Tregs within the total Treg pool independent of age ( Figure 1B ).

also in 24,539 other papers