The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model.

Nat Commun · 2025 · PMC11802874 · PMID 39915454

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did not reach statistical significanceno p-value reported

The effect of MI-883 on the total cholesterol concentration in the study did not reach statistical significance ( n = 5) even though there may be a tendency for a decrease in LDL and an increase in HDL cholesterol plasma concentrations (Supplementary Fig. 15 ).

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