Individualized resting-state functional connectivity abnormalities unveil two major depressive disorder subtypes with contrasting abnormal patterns of abnormality.

Transl Psychiatry · 2025 · PMC11802875 · PMID 39915482

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

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boldest claim

The sentences

approached significancep = 0.07so close (0.05 < p ≤ 0.1)

The two subtypes did not significantly differ in age, sex, illness duration, symptom severity, or ratios of first-episode and untreated cases, though the illness duration difference approached significance (subtype 1 vs. subtype 2, uncorrected p = 0.07, t = 1.79, df = 983, cohen’ d = 0.12).

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