Barely Significant
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The effect of nursing care provided to coronary intensive care patients according to their circadian rhythms on sleep quality, pain, anxiety, and delirium: a randomised controlled trial.

BMC Nurs · 2025 · PMC11804020 · PMID 39920733

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quite significantno p-value reported
In the light of this information, determining chronotypes and providing appropriate nursing care in terms of maintaining circadian rhythm, especially in intensive care patients, is quite significant in preventing pain, sleep problems, delirium, and many physiological issues and comorbid diseases.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.