Prognostic factors of thalamic and thalamopeduncular low-grade gliomas in children: A systematic review and recommendations for surgical management.

Brain Spine · 2025 · PMC11808518 · PMID 39931644

Europe PMC DOI

hedged sentences

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closest p

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boldest claim

The sentences

highly significantp < 00001a dropped decimal point

Reardon described bilateral involvement as a significant prognostic factor for a poorer 4-year PFS (p = 0.0016) and a highly significant factor for a poorer 4-year OS (p < 00001) ( Reardon et al., 1998 ).

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did not reach statistical significanceno p-value reported

However, the results either did not reach statistical significance or the analysis was not performed; probably due to the small sample size.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.