Evaluation of the Efficacy and Safety of On-Demand Tadalafil Alone or Combined With Lidocaine Spray for Treating Patients With Comorbid Erectile Dysfunction and Premature Ejaculation: A Randomized Controlled Trial.

Nevertheless, the CIPE-5 score results suggest that the active control group showed significant improvement in moderate to severe patients ( p < 0.001), while the experimental group did not reach statistical significance across all severity levels ( p > 0.05), leading to significant between-group differences ( F = 7.23, p = 0.001).

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