Female mice lacking GluA3 show early onset of hearing loss, cochlear synaptopathy, and afferent terminal swellings in ambient sound levels.

Although GluA4-only synapses were significantly greater in number in male GluA3 KO than WT raised in ambient conditions, 6 the differences did not reach statistical significance for the females (all synapses ambient, Figure 3 E, left; all synapses quiet; Figure 3 E, right).

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