Spatial proximity of CD8<sup>+</sup> T cells to tumor cells predicts neoadjuvant therapy efficacy in breast cancer.

NPJ Breast Cancer · 2025 · PMC11811209 · PMID 39929822

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a positive trendno p-value reported

did not reach statistical significanceno p-value reported

In HER-2-positive and TNBC subtypes, we observed a positive trend suggesting that higher percentages of N20-CD8 + T cells may correlate with better outcomes; however, these findings did not reach statistical significance, possibly due to limited sample sizes (Supplementary Fig. 13 ).

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