The near-significant difference in the volume ratio compared to the significant difference in overall and intra-cellular transverse relaxation times might be the result of intrinsic lower effect size compared to measurement error, but might potentially indicate the secondary effects of structural changes ( 51 ) following biochemical alteration ( 52 ).
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Understanding cellular proliferation activity in breast cancer using multi-compartment model of transverse relaxation time mapping on 3T MRI.
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