Improving cognitive impairment through chronic consumption of natural compounds/extracts: a systematic review and meta-analysis of randomized controlled trials.

Additionally, there was a notable trend toward improvement in MMSE scores after supplementation (SMD = 0.65, 95% CI 0.04 to 1.26, t 12 = 2.31, p = 0.04), also accompanied by significant heterogeneity ( I 2 = 91%, p < 0.01) ( Figure 4 ).

also in 1,375 other papers

Subgroup analyses focusing on terpenoids revealed a borderline significant improvement in ADAS-cog scores following supplementation (SMD = −2.20, 95% CI −4.34 to −0.06, t 5 = −2.65, p = 0.05) ( Figure 5 ), although substantial heterogeneity was observed ( I 2 = 98%, p < 0.01).

also in 2,347 other papers

Additionally, a suggestive trend toward improvement in MMSE scores was observed in a subgroup analysis of 1,717 participants (pooled standardized mean difference = 0.76, 95% CI: 0.06 to 1.46, t 18 = 2.27, p = 0.04).

also in 52 other papers