“a suggestive trend”

Additionally, there was a suggestive trend of correlation between disease duration exceeding 10 years and FC between the left lobule VIIb and the left calcarine (R = 0.43, p = 0.034).

Indeed, in control conditions there is a suggestive trend for a decline in sociability over time (effect of trial = −65.03 ± 31.45, F 1,19 = 4.28, p = 0.052) whereas fish measured under the risk context exhibit no such habituation (effect of trial = −37.8 ± 32.6, F 1,19 = 1.34, p = 0.26).

3c ), with a suggestive trend for decreased TERT expression for the VNTR6-1-Long allele (β = − 16.97 TPM, p = 0.053; Fig. 3d ).

Intermediate ADNC, P = 0.001), and a suggestive trend between Intermediate and High ADNC ( P = 0.055).

Furthermore, histomorphological assessment of plaques from the Athero-Express study cohort, encompassing parameters such as macrophage content, SMC content, collagen content, and calcification, revealed a suggestive trend towards heightened CCN2 expression in plaques exhibiting elevated levels of ACTA2 + SMC content ( P = 0.06), albeit not with other parameters ( Figure 7 E ).

The Q3 group also exhibited increased mortality at 1 month (aHR 1.94 [95% CI 1.07–3.5], p = 0.03), with a suggestive trend at 1 year but not reaching significance (aHR 1.50 [95% CI 0.98–2.30], p = 0.06).

However, we noticed that systemic MDA concentrations were significantly decreased following SCO administration in LOS pre-treated mice, as compared to the control group ( Figure 5 a, LOS + SCO versus Control, p = 0.043), and had a suggestive trend as compared to the injury-positive control (LOS + SCO versus SCO, p = 0.06), leading to the assumption that the angiotensin II receptors blockage could prevent SCO-induced lipid peroxidation traceable from the blood sera.

However, Neflamapimod treatment led to significantly reduced cerebrospinal fluid (CSF) levels compared to placebo, particularly in T-tau [difference (95% CI): -18.8 (-35.8, -1.8); P=0.031] and p-tau181 [-2.0 (-3.6, -0.5); P=0.012], with a suggestive trend for neurogranin [-21.0 (-43.6, 1.6); P=0.068].

Nevertheless, MFI values exhibited a noteworthy progressive increase over the experimental periods ( p < 0.001), with a suggestive trend ( p = 0.074) for the interaction between the diet and period.

With regards to EGFR TP53 comutations, there was a suggestive trend towards higher prevalence in women (42/69, 60.87% vs. 15/33, 45.45%, p= 0.2007; q= 0.2007) in HR+ NSCLC.

Reductions in visceral fat, FBS, TC, TG, and LDL were greater than placebo but not up to significant levels; simultaneously, there was a suggestive trend indicating improvement from baseline to week 8.

Although the ANOVA comparing NfL changes among ATN groups revealed only a suggestive trend towards significance (likely due to the limited sample size), post hoc analysis demonstrated that the rate of increase was more pronounced in patients with ATN+ status compared to those with isolated A+.

However, there was a suggestive trend towards reduced ischemic stroke incidence among females post-HP eradication, though this did not reach statistical significance.

On the other hand, there was a suggestive trend indicating that patients with high methylation levels of NKX6-1 might have an increased risk of developing MGL compared to those with lower methylation levels ( p = 0.062, Fig. 3 B), corresponding to a 1.7-fold increase in risk (HR = 1.73, 95% CI 0.80–3.75, p = 0.162, Table 2 ), which reached statistical significance considering the optimal cutoff value ( p = 0.021, Fig. 3 C, aHR = 2.01, 95% CI 0.93–4.33, p = 0.074, Table 2 ).

In our multivariable model, we observed a suggestive trend with higher risks among survivors receiving etoposide within the HSCT with TBI group.

In line with our results, a pan-cancer study indicated that obesity and overweight status were associated with improved PFS and OS after ICI therapy, with a suggestive trend in a small subgroup of EC patients ( 19 ).

Instead of a quantitative LGE assessment, we found a suggestive trend qualitatively that patients with LGE just localized at the apical cap less frequently had malignant arrhythmia compared to those with dense LGE extending toward the level of obstruction.

Additionally, the number of fusion segments also showed a suggestive trend toward interaction (p for interaction = 0.213), with patients undergoing multiple fusion segments having a slightly higher transfusion risk.

Furthermore, DLS size was positively (r = 0.916) correlated with β ATP in J774 cells when tested for all nanoforms (n = 6); however, when tested for only the uncoated nanoforms (n = 3), this association (r = −1.000) was significantly negative ( Table 4 ), while β ATP was positively correlated with total metal (r = 0.999) and Zn (r = 1.000) contents, and a suggestive trend of negative correlation (r = −0.994) is seen between βLDH and transition metal content ( Table 4 ). 3.4.

The NSGO-9501/EORTC-5591 trial demonstrated the efficacy of chemoradiation in improving outcomes for women predominantly diagnosed with Stage I endometrial cancer exhibiting Grade 3 and/or deep invasion.[ 13 ] This trial, along with the ongoing ManGO Iliade-III trial, pooled their data, revealing a significant enhancement in recurrence-free survival and a suggestive trend toward improved overall survival when chemotherapy was added to radiotherapy.

Results showed associations of RA with the use of five specific pesticides reported at AHS enrollment, including 3 insecticides (toxaphene, fonofos, and carbary) and 2 herbicides (atrazine, and chlorimuron ethyl) with notable findings for two pesticides with widespread use, including a significant trend for increasing cumulative days mixing or applying atrazine, an agricultural herbicide, and a suggestive trend for carbaryl, an insecticide with residential and agricultural applications.

89 Metabolomic profiling only revealed a suggestive trend of fecal L-Fucose in Atg16l1 ∆IEC mice at trimester 3, which may warrant further investigation due to the important role of fucosylation as a post-translational protein modification in Crohn’s disease and colorectal cancer. 26 , 90–92 We found consistent evidence for an increase in chitin-degradation in Atg16l1 ∆IEC pregnant mice in trimester 3 (day 18 after timed mating), both by higher abundance of the pathway in metagenomic data, as well as increased levels of its metabolite N-acetylglucosamine in the feces of these mice.

Some other prospective cohort study showed a suggestive trend of reduced glaucoma risk with higher intake of folate (vitamin B-9) i.e., compared with the lowest quintile of cumulatively averaged total folate intake, the MVRR of exfoliation glaucoma or glaucoma suspect for the highest quintile (Q5; ≥ 654 μg/day) was 0.75 (95% Confidence Interval [CI]: 0.54–1.04; p for linear trend = 0.02) ( 17 ).

However, we observed no substantial improvement in cognitive status as assessed by the Montreal Cognitive Assessment (MoCA) and the Mini‐Mental State Examination (MMSE), although there is a suggestive trend towards cognitive enhancement. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Collection date 2024 Dec.

There was a suggestive trend across the quintiles with Q5 showing the greatest decline in LDST performance.