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Hepatic GDP-fucose transporter SLC35C1 attenuates cholestatic liver injury and inflammation by inducing CEACAM1 N153 fucosylation.

Hepatology · 2025 · PMC11825483 · PMID 38985995

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We also detected higher levels of other inflammatory genes in the BDL livers, including Ccl4, Ccl7, Ccl20, Cxcl1, Cxcl15, Cxcl10, Cxcl11, Cxcl13, and Cxcl16, but the difference between Slc35c1 cKO -BDL livers and BDL-CTR livers did not reach statistical significance (Supplemental Figure S7C–K, http://links.lww.com/HEP/I541 ).

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