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PPIs effect in EGFR-TKI-associated interstitial lung diseases in patients with non-small cell lung cancer.

BMC Cancer · 2025 · PMC11827195 · PMID 39953451

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Our findings unveiled that the combination of lansoprazole or esomeprazole with EGFR-TKI was significantly associated with a higher reporting of ILD events, while the combination of other PPIs with EGFR-TKI therapy did not reach statistical significance (Table 2 ).

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