Remote Preconditioning Provides Protection Against Retinal Cell Death From Retinal Detachment.

Invest Ophthalmol Vis Sci · 2025 · PMC11827864 · PMID 39937497

Europe PMC DOI

hedged sentence

0.0626

closest p · 1.3× alpha

0.0626

boldest claim

The sentences

nearly significantP = 0.0626so close (0.05 < p ≤ 0.1)

We observed that preconditioning significantly diminished upregulation of Hmox (FC = 0.37, P = 0.0242), reduced the expression of Fas receptor mRNA, Fas (FC = 0.36, P = 0.0223), produced a nearly significant reduction in Fas ligand mRNA upregulation, Fasl (FC = 0.40, P = 0.0626), but did not affect Mlkl (FC = 1.01, P = 0.999) mRNA expression ( Figs. 4 P–S).

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