Barely Significant
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Ketamine does not rescue plaque load or gap detection in the 5XFAD mouse model of Alzheimer's disease.

Front Aging Neurosci · 2025 · PMC11830726 · PMID 39963471

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Ketamine may have slightly reduced amyloid plaques, but this effect was very small and did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.