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Effects of manual osteopathic interventions on psychometric and psychophysiological indicators of anxiety, depression and stress in adults: a systematic review and meta-analysis of randomised controlled trials.

BMJ Open · 2025 · PMC11831285 · PMID 39920074

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Clinically significant improvements (≥50% reduction on HARS) were observed in 57.1% of massage participants versus 35.3% in controls, although this difference did not reach statistical significance.

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