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Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs.

Cell Rep · 2025 · PMC11831618 · PMID 39786990

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We also observed a decrease in translation of the UAC tyrosine codon reporter in the TRMT1L-KO cell line, but this difference did not reach statistical significance ( Figure 7B , TRMT1L-KO).

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