A randomised double-blind, placebo-controlled trial of pramipexole in addition to mood stabilisers for patients with treatment-resistant bipolar depression (the PAX-BD study).

J Psychopharmacol · 2025 · PMC11831867 · PMID 39829389

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nearly significantno p-value reported

Coincident with this early effect of pramipexole, there was a nearly significant improvement in the ability to experience pleasure seen at 6 weeks (an increase of 2.04 points on the SHAPS: 95% CI: −0.11 to 4.20, d = −0.76), though not at 12 weeks.

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