Single-dose methylphenidate induces shift in functional connectivity associated with positive longer term clinical response in adult attention-deficit/hyperactivity disorder.

Sci Rep · 2025 · PMC11833068 · PMID 39962109

Europe PMC DOI

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0.0700

closest p · 1.4× alpha

0.0700

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The sentences

did not reach statistical significancep = .07so close (0.05 < p ≤ 0.1)

Compared to this baseline measure, rs-fc increased under MPH in individuals with ADHD, and we observed a difference between rs-fc ADHD (under MPH) and rs-fc neurotypicals, but this did not reach statistical significance ( p = .07) (Table S3 , Fig. 2 ).

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