Nicotinamide N-methyltransferase negatively regulates metastasis-promoting property of cancer-associated fibroblasts in lung adenocarcinoma.

Cancer Commun (Lond) · 2025 · PMC11833673 · PMID 39623600

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Within the established primary cultures of CAFs from LUADs, NNMT protein expression showed a trend of downregulation with advanced pathological stage and increased tumor size (Figure 3C ).

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