CDK6 kinase inhibition unmasks metabolic dependencies in BCR::ABL1+ leukemia.

Cell Death Dis · 2025 · PMC11836434 · PMID 39966356

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did not reach statistical significanceno p-value reported

In line with our concept, we detected elevated levels of pyruvic acid and lactic acid in Cdk6 KM/KM cells and to a lesser extent in Cdk6 −/− cells, using high-throughput metabolite analysis but the differences did not reach statistical significance (Fig. 5C ).

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