Dual α-globin-truncated erythropoietin receptor knockin restores hemoglobin production in α-thalassemia-derived erythroid cells.

GOrilla reports the FDR q-value of each GO term following Benjamini-Hochberg correction for multiple testing, and those GO processes with FDR ≤0.01 were considered to be highly significant.

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We found that the vector integrating the HBA1 transgene and HBA1 UTRs achieved the most highly HDR-edited population of erythroid cells (median of 63% YFP + cells; Figure 2D ) and the second highest MFI of the HDR-edited cell population ( Figure 2E ), although these changes did not reach statistical significance.

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