BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice.

Front Immunol · 2025 · PMC11839638 · PMID 39981256

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The frequencies of pulmonary MZB (B220+ CD93+ CD1d hi CD23 lo ) and their precursor (MZP; B220+ CD93+ CD1d hi CD23 hi ) cells increased significantly in the BCG+BAFF cohort and showed a trend toward increase in the BCG+APRIL cohort compared to the BCG-only cohort ( Figure 2B , Lungs).

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