iDC-targeting PfCSP mRNA vaccine confers superior protection against Plasmodium compared to conventional mRNA.

NPJ Vaccines · 2025 · PMC11840135 · PMID 39971939

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showed a trendno p-value reported

Sporozoite infection of the liver showed a trend towards enhanced protection of mice in both the groups compared to the first study (CSP mRNA: 62% vs 39.6% and MIP3α-CSP: 88% vs 72.5%) 42 h after challenge (Figs. 1H , 3H and Supplementary Fig. 4I ).

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