Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology.

Consistent with the histological findings, Alb Cre/+ ;Smn 2B/F7 mice showed variable triglycerides levels (n1=45.95, n2=10.10; n3=75.72; n4=21.91 μg/mg, mean ± SEM 38.44±14.48) ( Figure 2B ), and yet higher than those observed in +/+; Smn 2B/F7 controls (n1=2.60, n2=0.15; n3=0.66; n4=1.44 μg/mg, mean ± SEM 1.213±0.5332), although this difference did not reach statistical significance (p=0.0824).

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