Barely Significant
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Lack of cellular prion protein causes Amyloid β accumulation, increased extracellular vesicle abundance, and changes to exosome biogenesis proteins.

Mol Cell Biochem · 2025 · PMC11842432 · PMID 38970706

Europe PMCDOI
1
hedged sentence
0.0580
closest p · 1.2× alpha
0.0580
boldest claim

The sentences

a strong trendp = 0.058so close (0.05 < p ≤ 0.1)
At 48 h, the effect of oAβ challenge was more apparent, showing decreased Vps25 levels in all cell types, with a significant decrease in N2a-PRNP cells and a strong trend in PrP KO cells ( p = 0.058) (Fig. 1 D, E). nSMase2 and Rab31 showed similar results at both 6 h and 48 h (Fig. 1 D, F–H).

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