Yiqi Jianpi Kangai Decoction Enhances the Chemotherapy Effect by Inducing Apoptosis and Regulating Treg and Th17 Cells in Colorectal Cancer Mice Model with Spleen Qi Deficiency.

Compared with the spleen qi deficiency group after 21 days of gavage, the serum D-xylose content and amylase content also showed a decreasing trend, and the difference was significant ( P < .05), but the difference was not statistically significant ( P > .05) between the normal group after 21 and 30 days of gavage, which indicated that with the prolongation of senna gavage, the intestinal absorption capacity of the mice was weakened further ( Supplementary Table S5 , Figure 3C and D ).

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D-Xylulose and serum Amylase in Each Group of Mice The results of D-xylulose and serum amylase tests showed that compared with the normal group, the serum D-xylulose and amylase contents of the spleen qi deficiency group after 21 and 30 days of gavage were significantly reduced, and the differences were statistically significant ( P < .05); this indicated that the intestinal absorption ability of mice was weakened after senna gavage, and the model of spleen qi deficiency was successfully established; and the spleen qi deficiency group after 30 days of gavage showed a trend of reduction in serum D-xylulose and amylase contents when compared to the normal group after 21 and 30 days of gavage.

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