FTO inhibition mitigates high-fat diet-induced metabolic disturbances and cognitive decline in SAMP8 mice.

Mol Med · 2025 · PMC11843768 · PMID 39984825

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

a decreasing trendno p-value reported

A decreasing trend of insulin-like growth factor 1 ( Igf1) gene expression was observed in SAMP8 HFD FB23 mice (Fig. 7 A).

also in 47,180 other papers

a clear trendno p-value reported

Both decreased after FTO inhibition in the brain of SAMP8-HFD mice, with a clear trend for matrix metalloproteinase-2 (Mmp-2) and a significant difference for Mmp-9 (Fig. 7 J, K).

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.