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Placebo-Controlled Trials in the Management of Crohn's Disease: An Umbrella Review of Meta-Analyses.

Med Sci (Basel) · 2025 · PMC11843887 · PMID 39982236

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showed a trendno p-value reported
The clinical response rates seem to depend on dose according to some of the reviewed studies, and one study showed a trend towards mucosal healing (absence of ulceration) at week 12 in patients receiving adalimumab compared to placebo.

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