Role of tau versus TDP-43 pathology on medial temporal lobe atrophy in aging and Alzheimer's disease.

Alzheimers Dement · 2025 · PMC11846482 · PMID 39985478

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showed a trendno p-value reported

It is possible that these studies were underpowered to detect an effect of tau pathology, especially as several of these studies showed a trend association. 40 , 72 , 73 This still suggests that the effect of neurofibrillary pathology on neurodegeneration might be weaker than that of TDP‐43 pathology.

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