Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages.

Front Immunol · 2025 · PMC11850307 · PMID 40007543

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showed a trendno p-value reported

Comparison of the relative expression levels of the transcription factors; STAT-1 and IRF-5 (M1 macrophages) and STAT-6 and c-Maf (M2 Macrophages), between PM-positive and PM-negative placentas showed a trend toward lower expression for both M1- and M2-macrophage associated factors in infected placentas, with only statistical significance in the levels of STAT-6 expression.

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