Barely Significant
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Spermidine Supplementation Effectively Improves the Quality of Mouse Oocytes After Vitrification Freezing.

Antioxidants (Basel) · 2025 · PMC11852133 · PMID 40002410

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However, in this study, a tendency towards an increase in the level of reactive oxygen species in the mitochondria of mouse oocytes after freezing was observed, though this increase did not reach statistical significance.

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highly significantno p-value reported
The results of the present experiment demonstrated a highly significant decrease in intracellular glutathione levels after freezing, along with a significant increase in intracellular reactive oxygen species levels.

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