As shown in Figure 1 , after fully correcting for the previously mentioned covariates, the results showed a statistically significant U-shaped association for the eGFR ratio and the risk of AF recurrence ( p < 0.001); however, the associations between the eGFR ratio and the risk of adverse events ( p = 0.113) did not reach statistical significance ( Figure S2 in the Supplementary Materials ). 3.3.
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The association between the cystatin C- and creatinine-based estimated GFR ratio and post-ablation outcomes in patients with atrial fibrillation.
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The APPLE score, as a predictive model for AF recurrence, showed a decreasing trend among the four subgroups, which means that the probability of AF recurrence inferred from common risk factors gradually decreased. 3.2.