Neural indices of heritable impulsivity: Impact of the COMT Val158Met polymorphism on frontal beta power during early motor preparation.

Biol Psychol · 2024 · PMC11853962 · PMID 38862067

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0.0840

closest p · 1.7× alpha

0.0840

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a strong trendp = .084so close (0.05 < p ≤ 0.1)

Using linearly fitted slopes within the 0 to 110 ms time period, Val 158 homozygotes were confirmed to have an overall greater rate of beta decrease, or steeper downward slope, within the dACC-lh, F (1,40) = 12.3, p = .001, and a strong trend in the IFC-lh, F (1,40) = 3.1, p = .084 ( SI Fig. 1 ).

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