Single-Cell Sequencing Reveals the Role of Radiation-Induced Stemness-Responsive Cancer Cells in the Development of Radioresistance.

Int J Mol Sci · 2025 · PMC11855645 · PMID 40003899

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showed a trendno p-value reported

As shown in Figure 9 D,E, the A549-6Gy group showed a trend of an up-regulation of stem cell pluripotency-related pathways along with activation of the Hippo pathway compared with the A549-0Gy group and the A549-KD-6Gy group.

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a decreasing trendno p-value reported

We found that stem-like gene expression was significantly higher in the A549-6Gy group compared to the A549-Control group, presenting a decreasing trend with increasing doses, as shown in Figure 5 A–C.

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