Barely Significant
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The Relationship Between Thrombophilia and Modifications in First-Trimester Prenatal Screening Markers.

Medicina (Kaunas) · 2025 · PMC11857445 · PMID 40005435

Europe PMCDOI
4
hedged sentences
0.0790
closest p · 1.6× alpha
0.0790
boldest claim

The sentences

borderline significantp = 0.079so close (0.05 < p ≤ 0.1)
Parity emerges as the strongest predictor, showing a significant negative association with PAPP-A levels ( p = 0.026), while its effect on NT is weaker and only borderline significant ( p = 0.079).

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a possible trendno p-value reported
With 105 valid cases analyzed, this finding suggests a possible trend but lacks sufficient statistical evidence to confirm a strong or reliable association.

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nearing significanceno p-value reported
Parity showed a moderate negative trend (B = −0.250; p = 0.079), nearing significance but not conclusive.

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showed a trendno p-value reported
Non-smokers showed a trend toward lower risk of low PAPP-A, although the association was not statistically significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.