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HIV Cerebrospinal Fluid Escape: Interventions for the Management, Current Evidence and Future Perspectives.

Trop Med Infect Dis · 2025 · PMC11860496 · PMID 39998049

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The authors combined those taking three drugs—citalopram ( n = 24), trazodone ( n = 64) and sertraline ( n = 37)—that were trending towards significance into one category, the so-called “antiviral serotine reuptake inhibitors” and found that there was greater protection from detectable HIV RNA in the CSF (OR: 0.56, p = 0.02).

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