Ambient Air Pollution and Parkinson's Disease and Alzheimer's Disease: An Updated Meta-Analysis.

Toxics · 2025 · PMC11861764 · PMID 39997954

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marginally significantno p-value reported

Additionally, long-term NO 2 exposure was found to be associated with a marginally significant increase in the risk of PD.

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did not reach statistical significanceno p-value reported

The forest plot demonstrated that the pooled OR for the estimated effect of long-term PM 2.5 (per 5 μg/m 3 increase) exposure on AD was 1.16 (95% CI: 1.04, 1.30) ( Figure S1 ), and the pooled OR for the estimated effect of short-term PM 2.5 (per 5 μg/m 3 increase) exposure on AD did not reach statistical significance [OR: 1.02 (95% CI: 0.99, 1.05)] ( Figure S2 ).

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marginal significanceno p-value reported

The forest plots revealed that the pooled ORs for the estimated effects of long-term and short-term PM 2.5 (per 5 μg/m 3 increase) exposure on PD were 1.10 (95%CI: 1.03, 1.17) and 1.01 (95%CI: 1.002, 1.01) (marginal significance), respectively ( Figures S3 and S4 ). 3.2.2.

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