Barely Significant
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Advanced disease and CD8<sup>+</sup> TEMRA cells predict severe infections in multiple myeloma.

Front Immunol · 2025 · PMC11862831 · PMID 40013147

Europe PMCDOI
2
hedged sentences
0.0502
closest p · 1.0× alpha
0.0502
boldest claim

The sentences

a strong trendp = 0.05017so close (0.05 < p ≤ 0.1)
Of note, when investigating NDMM patients separately, we observed a strong trend towards higher CD8 + TEMRAs (p = 0.05017) as well as elevated IL-8 levels (p = 0.05036) in patients developing SI ( Supplementary Figure 2 ).

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highly significantno p-value reported
In the univariate analysis, we identified NDMM diagnosis compared to MGUS (p < 0.001), ISS stage II and III (p = 0.002), ECOG ≥ 2 (p < 0.001), and therapeutic intervention (p < 0.001) as highly significant clinical parameters.

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