Barely Significant
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Chronodisruption enhances inflammatory cytokine release from visceral adipose tissue in obesity.

J Transl Med · 2025 · PMC11863425 · PMID 40011933

Europe PMCDOI
2
hedged sentences
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

a negative trendp = 0.07so close (0.05 < p ≤ 0.1)
In contrast, BMAL1 mRNA levels demonstrated a negative correlation with MIP-1β ( p = 0.005) and a negative trend for IL-8 ( p = 0.07).

also in 1,305 other papers

a decreasing trendno p-value reported
As main findings, inflammatory markers in VAT, including IL-1β, IL-8, bFGF, MCP-1, and MIP-1β, showed a decreasing trend across chronotype groups, with the highest levels detected in evening chronotypes and the lowest in morning chronotypes, despite similar anthropometric, body composition, and biochemical parameters across the groups.

also in 18,548 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.