The association between early corticosteroid use and the risk of secondary infections in hospitalized patients with COVID-19: a double-edged sword. Results from the international SCCM discovery viral infection and respiratory illness universal study (VIRUS) COVID-19 registry.

Front Med (Lausanne) · 2025 · PMC11868930 · PMID 40027890

Europe PMC DOI

hedged sentence

0.4680

closest p · 9.4× alpha

0.4680

boldest claim

The sentences

did not reach statistical significancep -value = 0.468not close (p > 0.1)

However, the association with bacterial pneumonia and septic shock did not reach statistical significance in the adjusted model (OR 0.94, 95% CI 0.79–1.11, p -value = 0.468).

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