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Investigation in blood-brain barrier integrity and susceptibility to immune cell penetration in a mouse model of Dravet syndrome.

Brain Behav Immun Health · 2025 · PMC11869101 · PMID 40028233

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)
Thus, DS mice showed an evident motor hyperactivity measured in a computer-aided actimeter with elevated ambulation (t = 2.78, df = 28, p < 0.01), frequency of rears (t = 3.11, df = 28, p < 0.005), mean velocity (t = 2.03, df = 28, p < 0.05) and time spent in fast movements (t = 2.42, df = 28, p < 0.05), whereas their resting time showed a trend towards a reduction (t = 1.96, df = 28, p = 0.06) (see data in Supplementary File 1 ).

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