Roux-en-Y gastric bypass-associated fecal tyramine promotes colon cancer risk via increased DNA damage, cell proliferation, and inflammation.

Furthermore, we observed that in the tumor microenvironment NK cells were found to be lower and PMN-MDSCs displayed an increasing trend.

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Furthermore, a higher number of γH2AX + cells was noted in tyramine-treated Apc Min/ + compared to the untreated group but did not reach statistical significance (Fig. 6 h).

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