Barely Significant
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Involvement of propionate, citrulline, homoserine, and succinate in oral microbiome metabolite-driven periodontal disease progression.

Sci Rep · 2025 · PMC11871350 · PMID 40021789

Europe PMCDOI
1
hedged sentence
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

showed a trendP = 0.07so close (0.05 < p ≤ 0.1)
Treatment with 5-oxoproline, homoserine, propionate, and succinate significantly increased IL-8 mRNA expression compared with that in the control group, and treatment with N 1, N 12-diacetylspermine showed a trend of increasing IL-8 mRNA expression ( P = 0.07) (Table 5 ).

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