Exploring genetic loci linked to COVID-19 severity and immune response through multi-trait GWAS analyses.

Front Genet · 2025 · PMC11873281 · PMID 40034745

Europe PMC DOI

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closest p · 0.0× alpha

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boldest claim

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nominally significantP < 1.67 × 10−8actually significant

In our application, we prioritized nominally significant pleiotropic SNPs that achieved genome-wide significance ( P < 1.67 × 10−8) in the multi-trait analysis and suggestive significance ( P < 1 × 10 −3 ) in the original single-trait GWAS.

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