Exploration of the quantitative-effectiveness association between acupuncture temporal parameters and chemotherapy-induced peripheral neuropathy in cancer patients: a dose-response meta-analysis of randomized controlled trials.

Additionally, studies with a sample size (>15) showed significant pain improvement, while those with a smaller sample size (≤15) displayed weaker effects that did not reach statistical significance.

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Therefore, while lower to moderate doses of acupuncture show a decreasing trend in pain scores, this effect is not statistically significant; at higher doses, the pain relief effect stabilizes and becomes statistically significant Figure 7 .

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